In a pivotal experience while working as an intern at Philadelphia General Hospital in 1964, Marilyn Hughes Gaston, MD, admitted a baby with a swollen, infected hand. The baby suffered from sickle cell disease, which hadn’t occurred to Gaston until her supervisor suggested the possibility. Gaston quickly committed herself to learning more about it, and eventually became a leading researcher on the disease, which affects millions of people around the world. She became deputy branch chief of the Sickle Cell Disease Branch at the National Institutes of Health, and her groundbreaking 1986 study led to a national sickle cell disease screening program for newborns. Her research showed both the benefits of screening for sickle cell disease at birth and the effectiveness of penicillin to prevent infection from sepsis, which can be fatal in children with the disease.
In 1990, Gaston became the first black female physician to be appointed director of the Health Resources and Services Administration’s Bureau of Primary Health Care. She was also the second black woman to serve as assistant surgeon general as well as achieve the rank of rear admiral in the U.S. Public Health Service. Gaston has been honored with every award that the Public Health Service bestows.
